The IQWD1 Polyclonal Antibody (CAB14286) is a vital tool for researchers studying IQWD1, a protein involved in cell division and DNA replication processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for immunofluorescence and immunohistochemistry applications.IQWD1, also known as Intraflagellar Transport 52 Homolog, plays a crucial role in maintaining genomic stability and proper cell division. Dysregulation of IQWD1 has been linked to various diseases, including cancer and developmental disorders.
By using the IQWD1 Polyclonal Antibody, researchers can investigate the function and localization of IQWD1 in different cell types, providing valuable insights into its roles in cellular processes.Overall, the IQWD1 Polyclonal Antibody is a valuable tool for researchers interested in understanding the molecular mechanisms of DNA replication and cell division, with potential implications for therapeutic interventions targeting IQWD1-related diseases.
Product Name:
IQWD1 Rabbit Polyclonal Antibody
SKU:
CAB14286
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_001017977.1).
The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression.
Purification Method:
Affinity purification
Gene ID:
55827
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IQWD1 Rabbit pAb (CAB14286) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
