The IQGAP3 Polyclonal Antibody (CAB14197) is a valuable tool for studying IQGAP3, a scaffold protein involved in cell signaling and cytoskeletal dynamics. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically targets the IQGAP3 protein, allowing for accurate detection and analysis in various cell types.IQGAP3 is known to regulate processes such as cell migration, adhesion, and proliferation, making it a key player in cellular function and potentially a target for therapeutic interventions in diseases like cancer and cardiovascular disorders.
Research into the role of IQGAP3 can provide valuable insights into these conditions and facilitate the development of novel treatment strategies.By using the IQGAP3 Polyclonal Antibody, researchers can delve into the functions and interactions of IQGAP3 in different cellular contexts, contributing to advancements in understanding cell biology and disease mechanisms. Its reliability and specificity make it an essential component for studies in molecular biology and biomedical research.
Product Name:
IQGAP3 Rabbit Polyclonal Antibody
SKU:
CAB14197
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1437-1631 of human IQGAP3 (NP_839943.2).
Enables calmodulin binding activity and myosin VI light chain binding activity. Predicted to be involved in regulation of actin cytoskeleton organization. Predicted to act upstream of or within several processes, including intracellular signal transduction; positive regulation of macromolecule metabolic process; and positive regulation of mammary gland epithelial cell proliferation. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
128239
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using IQGAP3 antibody (CAB14197) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
