IQGAP2 Rabbit Polyclonal Antibody (CAB15392)
- SKU:
- CAB15392
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IQGAP2 Rabbit Polyclonal Antibody |
SKU: | CAB15392 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1330-1440 of human IQGAP2 (NP_006624.2). |
Sequence: | QQEV DHAT DMVS RAMI DSRT PEEM KHSQ SMIE DAQL PLEQ KKRK IQRN LRTL EQTG HVSS ENKY QDIL NEIA KDIR NQRI YRKL RKAE LAKL QQTL NALN KKAA FYEE QIN |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | IQGAP2 |
Positive Sample: | Jurkat,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | actin cytoskeleton, cell surface, cytoplasm, cytosol, extracellular exosome, filopodium, plasma membrane |
Calculated MW: | 181kDa |
Observed MW: | 180kDa |
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10788 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |