The IQGAP2 Polyclonal Antibody (CAB15392) is a valuable tool for researchers studying IQGAP2, a protein involved in cell signaling and cytoskeletal dynamics. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the IQGAP2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and cancer research.IQGAP2 is a scaffolding protein that plays a key role in cell proliferation, migration, and adhesion, making it a critical player in various cellular processes.
Dysregulation of IQGAP2 has been linked to tumorigenesis and metastasis in cancer, highlighting its importance as a potential therapeutic target. By investigating the function of IQGAP2 using this antibody, researchers can gain valuable insights into the mechanisms underlying cancer progression and identify new avenues for targeted therapy development.
Product Name:
IQGAP2 Rabbit Polyclonal Antibody
SKU:
CAB15392
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1330-1440 of human IQGAP2 (NP_006624.2).
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10788
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IQGAP2 Rabbit pAb (CAB15392) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
