IQGAP1 Rabbit Polyclonal Antibody (CAB5679)
- SKU:
- CAB5679
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | IQGAP1 Rabbit Polyclonal Antibody |
SKU: | CAB5679 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human IQGAP1 (NP_003861.1). |
Sequence: | ELMK LKAQ AHAE NNEF ITWN DIQA CVDH VNLV VQEE HERI LAIG LINE ALDE GDAQ KTLQ ALQI PAAK LEGV LAEV AQHY QDTL IRAK REKA QEIQ DESA VLWL DEIQ GGIW QSNK DTQE AQKF ALGI FAIN EAVE SGDV GKTL SALR SPDV GLYG VIPE CGET YHSD LAEA KKKK LAVG DNNS KWVK HWVK GGYY YYHN LETQ EGGW DEPP NFVQ NSMQ LSRE EIQS SISG VTAA YNRE QLWL ANEG LIT |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | SAR1; p195; HUMORFA01; IQGAP1 |
Positive Sample: | A-549,293T,HepG2,HT-29,HeLa,293F |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane. |
Calculated MW: | 189kDa |
Observed MW: | 189kDa/189kDa |
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Purification Method: | Affinity purification |
Gene ID: | 8826 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |