The IQCJ Antibody (PAC020402) is a polyclonal antibody specifically designed for research involving IQCJ, a protein that plays a critical role in various cellular processes. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in studies focused on understanding the function and regulation of IQCJ.Validated for use in Western blot applications, the IQCJ Antibody binds to the IQCJ protein, allowing for accurate detection and analysis in a variety of cell types.
This makes it a valuable tool for researchers in fields such as cell biology, molecular biology, and cancer research.IQCJ is known to be involved in processes related to cell migration, adhesion, and signaling pathways, making it an important target for studying diseases such as cancer and developmental disorders. By utilizing the IQCJ Antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Antibody Name:
IQCJ Antibody (PACO20402)
Antibody SKU:
PACO20402
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human IQCJ
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20402(IQCJ Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20402(IQCJ Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
IQCJ (IQ domain-containing protein J) is a 159 amino acid, protein that contains one IQ domain. Existing as four alternatively spliced isoforms, the gene encoding IQCJ maps to human chromosome 3q25.32. Chromosome 3 houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
Synonyms:
IQ motif containing J
UniProt Protein Function:
IQCJ: 5 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q25.32
