The IPP Polyclonal Antibody (PACO54310) is a powerful tool for researchers studying the activity of the immune checkpoint protein IPP (Imidazoquinoline Phosphoryl Polyprotein). This antibody, generated in rabbits, specifically targets IPP and is highly reactive with human samples. Validated for use in Western blot applications, the IPP Polyclonal Antibody enables the detection and analysis of IPP protein expression in various cell types.IPP is a key regulator of immune responses, particularly in the context of inflammation and infection.
Its role in immune modulation and potential as a therapeutic target in diseases such as cancer and autoimmune disorders make it a valuable molecule for investigation. By utilizing the IPP Polyclonal Antibody, researchers can further elucidate the functions of IPP in immunology and pave the way for the development of novel therapies targeting this checkpoint protein.
Western Blot. Positive WB detected in: Rat kidney tissue. All lanes: IPP antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 66 kDa. Observed band size: 66 kDa.
Immunofluorescent analysis of HepG2 cells using PACO54310 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO54310 at dilution of 1:100.
Background:
May play a role in organizing the actin cytoskeleton.
Synonyms:
Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27), IPP, KLHL27
UniProt Protein Function:
IPP: May play a role in organizing the actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 1p34-p32Cellular Component: cytoplasm; actin cytoskeletonMolecular Function: actin binding
