IPO8 Rabbit Polyclonal Antibody (CAB14679)
- SKU:
- CAB14679
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IPO8 Rabbit Polyclonal Antibody |
SKU: | CAB14679 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 878-1037 of human IPO8 (NP_006381.2). |
Sequence: | TRQL VNRE DRSK AEKA DMEE NEEI SSDE EETN VTAQ AMQS NNGR GEDE EEED DDWD EEVL EETA LEGF STPL DLDN SVDE YQFF TQAL ITVQ SRDA AWYQ LLMA PLSE DQRT ALQE VYTL AEHR RTVA EAKK KIEQ QGGF TFEN KGVL SAFN FGTV PSNN |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | VISS; RANBP8; IPO8 |
Positive Sample: | HeLa,Jurkat,Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 120kDa |
Observed MW: | 120kDa |
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10526 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |