The IPO13 Polyclonal Antibody (CAB16472) is a valuable tool for researchers studying IPO13, a protein involved in nuclear transport and regulation. This antibody, generated in rabbits, has high specificity and sensitivity for detecting IPO13 in human samples, making it ideal for use in immunohistochemistry and immunofluorescence experiments. By targeting IPO13, researchers can better understand its role in cellular processes such as protein import/export and gene expression regulation.IPO13, also known as Importin-13, is essential for the transport of proteins into the nucleus and plays a crucial role in maintaining cellular functions.
Dysregulation of IPO13 has been linked to various diseases, including cancer and neurological disorders, making it a promising target for therapeutic interventions. By studying IPO13 with this antibody, researchers can uncover new insights into its function and potential implications for disease development and treatment strategies.Overall, the IPO13 Polyclonal Antibody (CAB16472) is a versatile tool for investigating the role of IPO13 in cellular processes and disease pathogenesis, ultimately advancing research in fields such as cancer biology, neurobiology, and drug development.
Product Name:
IPO13 Rabbit Polyclonal Antibody
SKU:
CAB16472
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 764-963 of human IPO13 (NP_055467.3).
This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.
Purification Method:
Affinity purification
Gene ID:
9670
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using IPO13 Rabbit pAb (CAB16472) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
