The IPO11 Polyclonal Antibody (CAB14680) is a valuable tool for researchers studying IPO11, a key protein involved in nuclear transport processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the IPO11 protein, this antibody allows for the detection and analysis of IPO11 in various cell types, making it an essential resource for studies in cell biology and molecular biology.
IPO11 is an essential component of the nuclear transport machinery, playing a crucial role in the regulation of nucleocytoplasmic trafficking. Dysregulation of IPO11 has been implicated in various disease states, including cancer and neurodegenerative disorders. By investigating the function of IPO11, researchers can gain valuable insights into the molecular mechanisms underlying these conditions, potentially leading to the development of novel therapeutic strategies.
Product Name:
IPO11 Rabbit Polyclonal Antibody
SKU:
CAB14680
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 776-975 of human IPO11 (NP_057422.3).
Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).
Purification Method:
Affinity purification
Gene ID:
51194
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IPO11 Rabbit pAb (CAB14680) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
