The IP6K1 Polyclonal Antibody (CAB12216) is a valuable tool for researchers studying IP6K1, a key enzyme involved in cellular signaling pathways and regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the IP6K1 protein, this antibody enables accurate detection and analysis in a variety of cell types, allowing for in-depth research in areas such as cell signaling, metabolism, and disease mechanisms.
IP6K1, also known as inositol hexakisphosphate kinase 1, plays a crucial role in regulating cellular processes such as insulin signaling, cell growth, and autophagy. Dysregulation of IP6K1 has been linked to disorders including diabetes, cancer, and neurodegenerative diseases, highlighting its importance as a potential therapeutic target. By studying the function and expression of IP6K1, researchers can gain valuable insights into disease mechanisms and develop targeted therapies to address these conditions effectively.
Product Name:
IP6K1 Rabbit Polyclonal Antibody
SKU:
CAB12216
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human IP6K1 (NP_695005.1).
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
9807
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IP6K1 Rabbit pAb (CAB12216) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
