INVS Rabbit Polyclonal Antibody (CAB10298)
- SKU:
- CAB10298
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | INVS Rabbit Polyclonal Antibody |
SKU: | CAB10298 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human INVS (NP_055240.2). |
Sequence: | MNKS ENLL FAGS SLAS QVHA AAVN GDKG ALQR LIVG NSAL KDKE DQFG RTPL MYCV LADR LDCA DALL KAGA DVNK TDHS QRTA LHLA AQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | INV; NPH2; NPHP2; INVS |
Positive Sample: | 293T,K-562,Mouse liver,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, cilium, cytoskeleton, spindle. |
Calculated MW: | 118kDa |
Observed MW: | 120kDa |
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 27130 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |