The INTS8 Polyclonal Antibody (CAB17726) is a valuable tool for researchers studying the INTS8 protein, which is involved in DNA replication and repair processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.The INTS8 protein plays a crucial role in maintaining genomic stability and integrity, making it a key player in cell division and proliferation. Dysregulation of INTS8 has been linked to various diseases, including cancer, making it an attractive target for therapeutic intervention.
By utilizing the INTS8 Polyclonal Antibody, researchers can accurately detect and analyze the expression of INTS8 in different cell types, providing valuable insights into its function and dysregulation in disease states. This antibody serves as a reliable tool for studying DNA replication and repair mechanisms, offering new avenues for understanding disease pathogenesis and developing targeted therapies.
Product Name:
INTS8 Rabbit Polyclonal Antibody
SKU:
CAB17726
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human INTS8 (NP_060334.2).
This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55656
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using INTS8 Rabbit pAb (CAB17726) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
