The INTS7 Polyclonal Antibody (CAB16113) is a valuable tool for researchers studying INTS7, a crucial component of the Integrator complex involved in RNA processing and transcription regulation. This polyclonal antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the INTS7 protein, researchers can accurately detect and analyze its expression in various cell types, making this antibody ideal for studies in molecular biology, genetics, and oncology.
INTS7 is known for its role in RNA polymerase II transcription and small nuclear RNA processing, making it a key player in gene expression regulation. Dysregulation of INTS7 has been linked to various diseases, including cancer and developmental disorders, highlighting its importance in understanding cellular function and disease mechanisms. By using the INTS7 Polyclonal Antibody, researchers can gain valuable insights into the molecular pathways involving INTS7 and its implications in health and disease.
Product Name:
INTS7 Rabbit Polyclonal Antibody
SKU:
CAB16113
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 702-948 of human INTS7 (NP_001186740.1).
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
25896
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using INTS7 Rabbit pAb (CAB16113) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
