The INTS5 Polyclonal Antibody (CAB13646) is a valuable tool for studying the INTS5 protein, a component of the Integrator complex that plays a crucial role in RNA splicing and transcription regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the INTS5 protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for studies in molecular biology and gene regulation.INTS5 is known for its involvement in processing non-coding RNA molecules, as well as its potential role in gene expression regulation.
Dysregulation of INTS5 has been linked to various diseases, including cancer and neurological disorders. By studying the function of INTS5, researchers can gain valuable insights into the mechanisms underlying these conditions, potentially leading to the development of targeted therapies.Overall, the INTS5 Polyclonal Antibody is a valuable tool for researchers looking to explore the function of the INTS5 protein and its implications in disease pathogenesis. Its high specificity and reliability make it an essential component of any research project focused on RNA splicing and transcription regulation.
Product Name:
INTS5 Rabbit Polyclonal Antibody
SKU:
CAB13646
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human INTS5 (NP_085131.1).
The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex.
Purification Method:
Affinity purification
Gene ID:
80789
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using INTS5 Rabbit pAb (CAB13646) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
