The INTS14 Polyclonal Antibody (PACO39370) is a valuable tool for researchers studying the INTS14 protein, involved in chromatin remodeling and gene transcription regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.INTS14 is a key component of the Integrator complex, playing a crucial role in RNA processing and gene expression regulation. Dysregulation of INTS14 has been linked to various diseases, making it an attractive target for research in cancer, developmental disorders, and neurological conditions.
By detecting and analyzing INTS14 protein levels in different cell types, this antibody allows for a better understanding of its function and potential implications in disease pathology.With its high reactivity and specificity, the INTS14 Polyclonal Antibody is an essential tool for researchers investigating the intricate mechanisms of gene regulation and chromatin remodeling, offering insights into novel therapeutic strategies for targeting INTS14-related diseases.
Western blot. All lanes: INTS14 antibody at 4µg/ml. Lane 1: Hela whole cell lysate. Lane 2: NIH/3T3 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 58, 10, 49, 51 kDa. Observed band size: 58 kDa.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO39370 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO39370 at dilution of 1:100.
Synonyms:
Integrator complex subunit 14 (von Willebrand factor A domain-containing protein 9), INTS14, C15orf44 VWA9
UniProt Protein Function:
VWA9: Belongs to the UPF0464 family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 15q22.31