Intermediate capsid protein VP6 Antibody (PACO35206)
The Intermediate Capsid Protein VP6 Antibody (PACO35206) is a valuable tool for researchers studying viral infections, specifically targeting the VP6 protein found in rotavirus. This antibody, produced in rabbits, exhibits high reactivity with samples from various species and is validated for use in Western blotting and immunofluorescence applications.The VP6 protein is a major component of the rotavirus capsid and plays a crucial role in viral assembly and infectivity. By targeting VP6, researchers can better understand the dynamics of rotavirus infection and potentially develop new strategies for combatting this common cause of gastroenteritis in children.
With its specificity for VP6, the Intermediate Capsid Protein VP6 Antibody is an essential tool for investigations into the pathogenesis of rotavirus and the development of antiviral therapies. Its versatility in different assay formats makes it a valuable asset for virology and infectious disease research projects.
Antibody Name:
Intermediate capsid protein VP6 Antibody (PACO35206)
Antibody SKU:
PACO35206
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rotavirus A
Immunogen:
Recombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA)
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.
Synonyms:
Intermediate capsid protein VP6
UniProt Protein Function:
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP ().
