Intermediate capsid protein VP6 Antibody (PACO35198)
The Intermediate Capsid Protein VP6 Antibody (PAC035198) is a valuable tool for researchers studying the VP6 protein, a component of rotavirus, a major cause of severe diarrhea in children worldwide. This polyclonal antibody, produced through immunization of rabbits, exhibits high reactivity with samples from various species and is validated for use in techniques such as Western blotting.VP6 is an essential structural protein in the rotavirus capsid, playing a crucial role in viral assembly and replication. Research on VP6 is important for understanding the pathogenesis of rotavirus infections and developing effective vaccines and antiviral therapies.
The Intermediate Capsid Protein VP6 Antibody facilitates the detection and analysis of VP6 in cell samples, making it a valuable tool for studies in virology and vaccine development.By targeting the VP6 protein, researchers can gain insights into the mechanisms of rotavirus infection and immune responses, ultimately contributing to the prevention and treatment of rotavirus-related diseases. The Intermediate Capsid Protein VP6 Antibody is a versatile tool for investigating the role of VP6 in viral pathogenesis and developing strategies to combat rotavirus infections.
Antibody Name:
Intermediate capsid protein VP6 Antibody (PACO35198)
Antibody SKU:
PACO35198
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rotavirus A
Immunogen:
Recombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA)
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.
Synonyms:
Intermediate capsid protein VP6
UniProt Protein Function:
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP ().
