The Interleukin-6 Polyclonal Antibody (CAB0286) is specifically designed for research involving Interleukin-6, a cytokine that plays a critical role in inflammation and immune response regulation. The antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in a variety of applications, including Western blotting. By binding to the Interleukin-6 protein, this antibody enables researchers to detect and analyze the presence of Interleukin-6 in different cell types, making it an ideal tool for studies in immunology, inflammation, and cancer research.
Interleukin-6 is a key mediator of the inflammatory response and has been implicated in a wide range of diseases, including autoimmune disorders, cardiovascular diseases, and cancer. By targeting Interleukin-6, researchers can gain valuable insights into the mechanisms underlying these diseases and develop novel therapeutic strategies to target this cytokine for treatment. The Interleukin-6 Polyclonal Antibody (CAB0286) is a valuable tool for researchers looking to explore the role of Interleukin-6 in disease pathogenesis and develop new therapies to target this important cytokine.
Product Name:
IL6 Rabbit Polyclonal Antibody
SKU:
CAB0286
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 30-212 of human IL6 (NP_000591.1).
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).
Purification Method:
Affinity purification
Gene ID:
3569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL6 Rabbit pAb (CAB0286) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
