The Interleukin-33 Polyclonal Antibody (CAB8096) is a valuable tool for researchers studying interleukin-33 (IL-33), a crucial cytokine involved in inflammatory and immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to IL-33, researchers can accurately detect and analyze the protein in various cell types, making it an excellent choice for studies in immunology, allergy, and inflammation research.IL-33 is known for its role in regulating immune responses, particularly in promoting the activation of immune cells and inflammation.
Research has shown that dysregulation of IL-33 signaling is associated with various diseases, including asthma, autoimmune disorders, and inflammatory conditions. By studying the function of IL-33 using this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop novel therapeutic strategies targeting IL-33 signaling pathways.
Product Name:
IL33 Rabbit Polyclonal Antibody
SKU:
CAB8096
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human IL33 (NP_254274.1).
The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
90865
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL33 antibody (CAB8096) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
