The Interleukin-25 Polyclonal Antibody (CAB8252) is specifically designed for research involving interleukin-25 (IL-25), a cytokine that plays a crucial role in regulating immune responses, inflammation, and allergic reactions. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blotting.IL-25, also known as IL-17E, is a key player in the immune system, promoting the production of other inflammatory cytokines and immune cells. It is involved in protective immunity, allergic inflammation, and tissue repair processes.
The Interleukin-25 Polyclonal Antibody binds to the IL-25 protein, allowing for its detection and analysis in different cell types.By studying the activity of IL-25, researchers can gain insights into the mechanisms underlying immune responses and inflammatory conditions. This antibody is an essential tool for studying the role of IL-25 in various diseases, including asthma, autoimmune disorders, and cancer. Its versatility and specificity make it ideal for immunology and cancer research studies.
Product Name:
IL25 Rabbit Polyclonal Antibody
SKU:
CAB8252
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-177 of human IL25 (NP_073626.1).
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
64806
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with 17E/IL25 using IL25 Rabbit pAb (CAB8252) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
