The Interleukin-22 Polyclonal Antibody (CAB6216) is a valuable tool for researchers studying the role of interleukin-22 (IL-22) in immune responses and inflammatory conditions. Interleukin-22 is a cytokine that plays a crucial role in the regulation of tissue homeostasis and the defense against pathogens.This antibody, generated in rabbits, is highly specific for IL-22 and has been validated for use in Western blot applications. It binds specifically to IL-22, allowing for the detection and analysis of IL-22 in various cell types and tissue samples.IL-22 has been implicated in a variety of immune-related diseases, including inflammatory bowel disease, psoriasis, and cancer.
By studying the activity of IL-22 using this antibody, researchers can gain valuable insights into the role of this cytokine in disease pathogenesis and potentially identify new therapeutic targets for these conditions.Overall, the Interleukin-22 Polyclonal Antibody (CAB6216) is a reliable tool for researchers looking to investigate the function of IL-22 in immune regulation and inflammatory diseases. Its high specificity and sensitivity make it a valuable addition to any immunology or cancer research laboratory.
Product Name:
IL22 Rabbit Polyclonal Antibody
SKU:
CAB6216
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 34-179 of human IL22 (NP_065386.1).
This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. The encoded protein is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2).
Purification Method:
Affinity purification
Gene ID:
50616
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from HL-60 cells, using IL22 Rabbit pAb (CAB6216) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
