The Interleukin-21 Polyclonal Antibody (CAB7235) is a valuable tool for researchers studying interleukin-21, a cytokine known for its role in immune cell regulation and inflammation. This antibody, produced using rabbit immunization, is highly specific for detecting interleukin-21 in human samples and is validated for use in Western blotting applications.Interleukin-21 is a key player in the immune response, influencing various cell types such as T cells, B cells, and natural killer cells. Its dysregulation has been implicated in autoimmune diseases, cancer, and inflammatory conditions, highlighting its importance in biomedical research.
By using this antibody to detect interleukin-21, researchers can gain insights into its function and potential therapeutic applications in immune-related disorders.Overall, the Interleukin-21 Polyclonal Antibody (CAB7235) is a reliable tool for researchers investigating the role of interleukin-21 in immune modulation and disease pathogenesis. Its specificity and sensitivity make it a valuable asset in studies aimed at understanding and targeting interleukin-21 in various pathological conditions.
Product Name:
IL21 Rabbit Polyclonal Antibody
SKU:
CAB7235
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-162 of human IL21 (NP_068575.1).
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
59067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB7235) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
