IL13 Rabbit Polyclonal Antibody (CAB2089)
- SKU:
- CAB2089
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL13 Rabbit Polyclonal Antibody |
SKU: | CAB2089 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-146 of human IL13 (NP_002179.2). |
Sequence: | LTCL GGFA SPGP VPPS TALR ELIE ELVN ITQN QKAP LCNG SMVW SINL TAGM YCAA LESL INVS GCSA IEKT QRML SGFC PHKV SAGQ FSSL HVRD TKIE VAQF VKDL LLHL KKLF REGQ FN |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | P600; IL-13; IL13 |
Positive Sample: | U-937,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 16kDa |
Observed MW: | 16kDa |
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Purification Method: | Affinity purification |
Gene ID: | 3596 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |