The Interleukin-11 Polyclonal Antibody (CAB1902) is a valuable tool for researchers studying Interleukin-11, a cytokine involved in various biological processes such as inflammation, hematopoiesis, and osteoclast differentiation. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Interleukin-11 protein, it enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology, oncology, and other research areas.Interleukin-11 is known for its diverse roles in both physiological and pathological conditions, including its involvement in cancer progression, bone metabolism, and inflammatory disorders.
As a key mediator in these processes, understanding the function and regulation of Interleukin-11 is essential for developing targeted therapies and interventions for diseases where its dysregulation plays a significant role. The Interleukin-11 Polyclonal Antibody offers researchers a reliable tool to explore the complex mechanisms underlying Interleukin-11 signaling and its implications in disease pathogenesis.
Product Name:
IL11 Rabbit Polyclonal Antibody
SKU:
CAB1902
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-199 of human IL11 (NP_000632.1).
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3589
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL11 Rabbit pAb (CAB1902) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
