The Interferon Lambda-3 Polyclonal Antibody (CAB5648) is a specialized research tool designed for the study of Interferon Lambda-3, a type of interferon that plays a crucial role in the immune response against viral infections. This antibody, produced in rabbits, demonstrates high specificity and reactivity with human samples, making it an ideal choice for researchers working in immunology and virology.Interferon Lambda-3, also known as IFNL3, is a key player in the antiviral immune response, particularly in the case of hepatitis C virus infections. By targeting the IFNL3 protein, this antibody allows for the detection and analysis of Interferon Lambda-3 in various cell types, providing valuable insights into its role in viral defense mechanisms.
Research into Interferon Lambda-3 is essential for the development of new antiviral therapies and the understanding of immune responses to viral infections. The IFNL3 Polyclonal Antibody serves as a valuable tool for unraveling the complex mechanisms involved in the immune system's defense against viruses, paving the way for innovative treatments and strategies in the field of infectious diseases.
Product Name:
IFNL3 Rabbit Polyclonal Antibody
SKU:
CAB5648
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFNL3 (NP_742151.2).
Recombinant Human IFNL3 Protein,K-562,Mouse thymus
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
22kDa
Observed MW:
24kDa
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Purification Method:
Affinity purification
Gene ID:
282617
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse thymus, using IFNL3 Rabbit pAb (CAB5648) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
