The Interferon Lambda-1 Polyclonal Antibody (CAB8288) is a valuable tool for researchers studying interferon lambda-1, a type III interferon involved in antiviral immunity. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to interferon lambda-1, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in virology and immunology.Interferon lambda-1 plays a crucial role in the innate immune response to viral infections, activating antiviral defenses to limit viral replication and spread.
Its unique mechanism of action and distinct receptor distribution make it an intriguing target for studying immune responses to viral pathogens. By elucidating the functions of interferon lambda-1, researchers can uncover new insights into antiviral immunity and potentially identify novel therapeutic strategies for viral diseases.Overall, the Interferon Lambda-1 Polyclonal Antibody (CAB8288) offers researchers a reliable tool for investigating the role of interferon lambda-1 in antiviral immunity, providing valuable insights into immune responses against viral infections and opening new avenues for therapeutic development.
Product Name:
IFNL1 Rabbit Polyclonal Antibody
SKU:
CAB8288
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human IFNL1 (NP_742152.1).
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Purification Method:
Affinity purification
Gene ID:
282618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IFNL1 Rabbit pAb (CAB8288) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 20s.
