Integrin linked ILK Rabbit Monoclonal Antibody (CAB4571)
The Integrin-linked ILK Rabbit Monoclonal Antibody (CAB4571) is a powerful tool for research involving integrin-linked kinase (ILK), a key player in cell adhesion and signaling pathways. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ILK in human samples, making it ideal for Western blot applications.ILK is a multifunctional protein that plays a crucial role in cell adhesion, migration, and survival. It is involved in various cellular processes, including cytoskeletal organization, gene expression, and cell proliferation.
Dysregulation of ILK has been implicated in cancer progression, making it a promising target for cancer research and therapy development.By targeting ILK with the CAB4571 antibody, researchers can gain valuable insights into the molecular mechanisms underlying cell adhesion and signaling pathways. This antibody is a valuable tool for studying the roles of ILK in normal cellular processes and disease states, paving the way for potential therapeutic interventions targeting ILK in cancer and other related conditions.
Product Name:
Integrin linked ILK Rabbit Monoclonal Antibody
SKU:
CAB4571
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-452 of human Integrin linked ILK (Q13418).
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3611
Clone Number:
ARC1037
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Integrin linked ILK Rabbit mAb (CAB4571) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
