Integrin beta 4 (ITGB4/CD104) Rabbit Polyclonal Antibody (CAB0857)
- SKU:
- CAB0857
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | Integrin beta 4 (ITGB4/CD104) Rabbit Polyclonal Antibody |
SKU: | CAB0857 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 611-710 of human Integrin beta 4 (ITGB4/CD104) (NP_000204.3). |
Sequence: | DTIC EINY SAIH PGLC EDLR SCVQ CQAW GTGE KKGR TCEE CNFK VKMV DELK RAEE VVVR CSFR DEDD DCTY SYTM EGDG APGP NSTV LVHK KKDC PPGS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CD104; GP150; JEB5A; JEB5B; Integrin beta 4 (ITGB4/CD104) |
Positive Sample: | PC-3,Mouse colon,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Lipid-anchor, Single-pass type I membrane protein, hemidesmosome. |
Calculated MW: | 202kDa |
Observed MW: | 202kDa |
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3691 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |