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Integrin beta 3 (ITGB3/CD61) Rabbit Monoclonal Antibody (CAB19073)

SKU:
CAB19073
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Integrin beta 3 (ITGB3/CD61) Rabbit Monoclonal Antibody
SKU:CAB19073
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 689-788 of human Integrin beta 3 (ITGB3/CD61) (P05106).
Sequence:CVVR FQYY EDSS GKSI LYVV EEPE CPKG PDIL VVLL SVMG AILL IGLA ALLI WKLL ITIH DRKE FAKF EEER ARAK WDTA NNPL YKEA TSTF TNIT YRGT
Tested Applications:WB IHC-P IP ELISA FC (intra)
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsFC (intra),1:50 - 1:200
Synonyms:GT; GT2; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; BDPLT24; Integrin beta 3 (ITGB3/CD61)
Positive Sample:U-87MG,HUVEC,Mouse lung
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, focal adhesion, lamellipodium membrane.
Calculated MW:87kDa
Observed MW:110kDa

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Purification Method:Affinity purification
Gene ID:3690
Clone Number:ARC0460
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Integrin beta 3 (ITGB3/CD61) Rabbit mAb (CAB19073) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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