The Integrin Beta 3 Rabbit Monoclonal Antibody (CAB19073) is a high-quality antibody designed for research involving Integrin Beta 3, a cell surface receptor involved in cell adhesion and signaling. This antibody, produced in rabbits, offers high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the Integrin Beta 3 protein, allowing for detection and analysis in various cell types.Integrin Beta 3 is known for its role in cell adhesion and migration, making it an important target for studies in cell biology, cancer research, and angiogenesis.
By understanding the function and regulation of Integrin Beta 3, researchers can gain insights into processes such as tumor metastasis, platelet aggregation, and angiogenesis. This antibody is a valuable tool for investigating the role of Integrin Beta 3 in various physiological and pathological processes, providing valuable insights for drug discovery and therapeutic development.
Cell junction, Cell membrane, Cell projection, Single-pass type I membrane protein, focal adhesion, lamellipodium membrane.
Calculated MW:
87kDa
Observed MW:
110kDa
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Purification Method:
Affinity purification
Gene ID:
3690
Clone Number:
ARC0460
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Integrin beta 3 (ITGB3/CD61) Rabbit mAb (CAB19073) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
