The Integrin Beta 2 Polyclonal Antibody (CAB2173) is a vital tool for researchers studying Integrin Beta 2, an essential cell adhesion molecule involved in immune responses and inflammation. This antibody, produced in rabbits, has high specificity and sensitivity for human samples, making it ideal for use in Western blot applications. By targeting the Integrin Beta 2 protein, researchers can accurately detect and analyze its expression in a variety of cell types, facilitating studies in immunology and cancer research.Integrin Beta 2, also known as CD18, plays a crucial role in cell adhesion and migration, making it a key player in immune cell function and inflammatory processes.
Dysregulation of Integrin Beta 2 has been implicated in various diseases, including immune deficiencies and inflammatory disorders. By understanding the function of Integrin Beta 2, researchers can gain insights into potential therapeutic targets for conditions such as autoimmune diseases and cancer.Overall, the Integrin Beta 2 Polyclonal Antibody (CAB2173) is a valuable tool for researchers looking to delve into the mechanisms of immune cell adhesion and inflammation, ultimately contributing to the development of novel therapies for a range of immune-related diseases.
Product Name:
CD18 Rabbit Polyclonal Antibody
SKU:
CAB2173
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-125 of CD18 (NP_000202.3).
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3689
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD18 Rabbit pAb (CAB2173) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
