The Integrin Beta 1 Polyclonal Antibody (CAB2217) is a valuable tool for researchers studying integrin beta 1, a key cell adhesion molecule involved in cell signaling and migration. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to integrin beta 1, this antibody allows for the detection and analysis of this important protein in various cell types, making it ideal for studies in cell biology, developmental biology, and cancer research.Integrin beta 1 plays a crucial role in cell adhesion and signaling, mediating cell-to-cell and cell-to-extracellular matrix interactions.
Dysregulation of integrin beta 1 has been implicated in various diseases, including cancer, inflammatory disorders, and developmental abnormalities. By studying the function and expression of integrin beta 1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the Integrin Beta 1 Polyclonal Antibody (CAB2217) is a valuable tool for researchers investigating the role of integrin beta 1 in health and disease. Its high specificity, sensitivity, and reliability make it a dependable reagent for a wide range of research applications.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3688
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Integrin-β1/CD29 antibody (CAB2217) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
