The Integrin Alpha X Polyclonal Antibody (CAB1508) is a valuable tool for researchers studying integrin alpha X, a cell adhesion molecule involved in various cellular processes, including cell migration and interaction with immune cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the integrin alpha X protein, this antibody enables the detection and analysis of integrin alpha X in different cell types, making it an ideal choice for studies in immunology, inflammation, and cancer research.
Integrin alpha X plays a crucial role in mediating cell adhesion and migration, particularly in immune responses and inflammatory processes. Its involvement in cell-cell interactions and regulation of immune cell function highlights its significance as a potential therapeutic target in diseases such as cancer, autoimmune disorders, and inflammatory conditions. By investigating the function and expression of integrin alpha X, researchers can gain insights into its role in disease pathogenesis and potentially develop novel treatment strategies targeting this molecule.
Product Name:
ITGAX Rabbit Polyclonal Antibody
SKU:
CAB1508
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 146-342 of ITGAX (NP_000878.2).
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3687
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from THP-1 cells, using ITGAX Rabbit pAb (CAB1508) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
