Integrin alpha V (ITGAV/CD51) Rabbit Monoclonal Antibody (CAB19071)
The Integrin Alpha V Rabbit Monoclonal Antibody (CAB19071) is a valuable tool for researchers studying integrin alpha V, a cell surface receptor involved in cell adhesion and signaling. This antibody, raised in rabbits, specifically targets the integrin alpha V protein, enabling precise detection and analysis in a variety of cell types.Integrin alpha V is known to play a critical role in processes such as cell migration, proliferation, and survival, making it a key target for studies in cell biology and cancer research. This antibody is validated for use in Western blot applications, providing researchers with a reliable tool for investigating the function and regulation of integrin alpha V in various biological contexts.
By using the Integrin Alpha V Rabbit Monoclonal Antibody (CAB19071), researchers can gain insights into the molecular mechanisms underlying integrin alpha V-mediated cellular processes, paving the way for the development of novel therapeutic strategies targeting integrin alpha V in diseases such as cancer and inflammation.
Product Name:
Integrin alpha V (ITGAV/CD51) Rabbit Monoclonal Antibody
SKU:
CAB19071
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 949-1048 of human Integrin alpha V (ITGAV/CD51) (NP_002201.2).
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Purification Method:
Affinity purification
Gene ID:
3685
Clone Number:
ARC50621
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Integrin alpha V (ITGAV/CD51) Rabbit mAb (CAB19071) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
