Integrin alpha V (ITGAV/CD51) Rabbit Polyclonal Antibody (CAB2091)
- SKU:
- CAB2091
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Integrin alpha V (ITGAV/CD51) Rabbit Polyclonal Antibody |
SKU: | CAB2091 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 950-1048 of human Integrin alpha V (ITGAV/CD51) (NP_002201.1). |
Sequence: | LKSS ASFN VIEF PYKN LPIE DITN STLV TTNV TWGI QPAP MPVP VWVI ILAV LAGL LLLA VLVF VMYR MGFF KRVR PPQE EQER EQLQ PHEN GEGN SET |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | CD51; MSK8; VNRA; VTNR; Integrin alpha V (ITGAV/CD51) |
Positive Sample: | MCF7,NIH/3T3,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 116kDa |
Observed MW: | 130kDa |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Purification Method: | Affinity purification |
Gene ID: | 3685 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |