CD11a/LFA-1A/ITGAL Rabbit Polyclonal Antibody (CAB1644)
- SKU:
- CAB1644
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CD11a/LFA-1A/ITGAL Rabbit Polyclonal Antibody |
SKU: | CAB1644 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-340 of human CD11a/LFA-1A/ITGAL (NP_001107852.1). |
Sequence: | YNLD VRGA RSFS PPRA GRHF GYRV LQVG NGVI VGAP GEGN STGS LYQC QSGT GHCL PVTL RGSN YTSK YLGM TLAT DPTD GSIL FAAV QFST SYKT EFDF SDYV KRKD PDAL LKHV KHML LLTN TFGA INYV ATEV FREE LGAR PDAT KVLI IITD GEAT DSGN IDAA KDII RYII GIGK HFQT KESQ ETLH KFAS KPAS EFVK ILDT FEKL KDLF TELQ KKIY VIEG TSKQ DLTS FNME LSSS GISA DLSR GHAV VGAV GAKD WAGG FLDL KADL QDDT FIGN EPLT PEVR AGYL GYTV TWLP SRQK TSLL ASG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | CD11A; LFA-1; LFA1A; CD11a/LFA-1A/ITGAL |
Positive Sample: | Molt-4,Mouse spleen,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 129kDa |
Observed MW: | 180kDa |
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3683 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |