The Integrin Alpha 4 Rabbit Monoclonal Antibody (CAB4054) is a cutting-edge tool for researchers studying integrin alpha 4, a key cell surface receptor involved in cell adhesion, migration, and signaling processes. This high-quality antibody, developed using rabbit monoclonal technology, exhibits strong reactivity with human samples and is optimized for use in Western blot and immunohistochemistry applications.Integrin alpha 4 plays a crucial role in various physiological and pathological processes, including immune cell trafficking, inflammation, and cancer metastasis.
By targeting integrin alpha 4 with this specific antibody, researchers can effectively visualize and analyze the expression and localization of this protein in different cell types, providing valuable insights into its function and potential therapeutic implications.With its exceptional specificity and sensitivity, the Integrin Alpha 4 Rabbit Monoclonal Antibody (CAB4054) is an indispensable tool for investigating the role of integrin alpha 4 in various biological processes, making it an invaluable asset for studies in immunology, oncology, and cell biology.
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3676
Clone Number:
ARC0888
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Integrin alpha 4 (ITGA4/CD49d) (ITGA4/CD49d) Rabbit mAb (CAB4054) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
