Integrin alpha 4 (ITGA4/CD49d) Rabbit Monoclonal Antibody (CAB4054)
- SKU:
- CAB4054
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Integrin alpha 4 (ITGA4/CD49d) Rabbit Monoclonal Antibody |
SKU: | CAB4054 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 933-1032 of human Integrin alpha 4 (ITGA4/CD49d) (P13612). |
Sequence: | ALKF EIRA TGFP EPNP RVIE LNKD ENVA HVLL EGLH HQRP KRYF TIVI ISSS LLLG LIVL LLIS YVMW KAGF FKRQ YKSI LQEE NRRD SWSY INSK SNDD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | IA4; CD49D; Integrin alpha 4 (ITGA4/CD49d) |
Positive Sample: | Jurkat,Mouse spleen,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 115kDa |
Observed MW: | 70kDa/140kDa/150kDa/200kDa |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3676 |
Clone Number: | ARC0888 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |