Integrin alpha 4 (ITGA4/CD49d) Rabbit Polyclonal Antibody (CAB0696)
- SKU:
- CAB0696
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Integrin alpha 4 (ITGA4/CD49d) Rabbit Polyclonal Antibody |
SKU: | CAB0696 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 770-970 of human Integrin alpha 4 (ITGA4/CD49d) (NP_000876.3). |
Sequence: | LKYE VKLT VHGF VNPT SFVY GSND ENEP ETCM VEKM NLTF HVIN TGNS MAPN VSVE IMVP NSFS PQTD KLFN ILDV QTTT GECH FENY QRVC ALEQ QKSA MQTL KGIV RFLS KTDK RLLY CIKA DPHC LNFL CNFG KMES GKEA SVHI QLEG RPSI LEMD ETSA LKFE IRAT GFPE PNPR VIEL NKDE NVAH VLLE GLHH Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IA4; CD49D; Integrin alpha 4 (ITGA4/CD49d) |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 115kDa |
Observed MW: | 70kDa/140kDa/150kDa |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3676 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |