The Integrin Alpha 2 Rabbit Monoclonal Antibody (CAB19068) is a vital tool for researchers studying integrin alpha 2, a cell surface protein involved in cell adhesion and migration processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the integrin alpha 2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for investigations in cell biology, cancer research, and immunology.Integrin alpha 2 is a key player in cell adhesion and migration, influencing processes such as wound healing, tissue remodeling, and tumor metastasis.
Its role in regulating cell behavior makes it a promising target for research into diseases like cancer, cardiovascular disorders, and fibrosis. Understanding the function of integrin alpha 2 is essential for developing therapies that target aberrant cell adhesion and migration in these pathological conditions.Overall, the Integrin Alpha 2 Rabbit Monoclonal Antibody (CAB19068) is a valuable tool for researchers interested in unraveling the complex mechanisms of integrin alpha 2 and its implications in various physiological and pathological processes. Its high specificity and sensitivity make it an ideal choice for studies aiming to elucidate the role of integrin alpha 2 in health and disease.
293T,A549,Mouse large intestine,Mouse lung,Mouse spleen,Rat lung
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Single-pass type I membrane protein.
Calculated MW:
129kDa
Observed MW:
150kDa
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3673
Clone Number:
ARC0457
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from A549 cells, using [KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit mAb (CAB19068) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
