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Integrin alpha 2 (ITGA2/CD49b) Rabbit Monoclonal Antibody (CAB19068)

SKU:
CAB19068
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Integrin alpha 2 (ITGA2/CD49b) Rabbit Monoclonal Antibody
SKU:CAB19068
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1082-1181 of human Integrin alpha 2 (ITGA2/CD49b) (P17301).
Sequence:GTFA SSTF QTVQ LTAA AEIN TYNP EIYV IEDN TVTI PLMI MKPD EKAE VPTG VIIG SIIA GILL LLAL VAIL WKLG FFKR KYEK MTKN PDEI DETT ELSS
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; b)
Positive Sample:293T,A549,Mouse large intestine,Mouse lung,Mouse spleen,Rat lung
Conjugate:Unconjugated
Cellular Localization:Membrane, Single-pass type I membrane protein.
Calculated MW:129kDa
Observed MW:150kDa

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:3673
Clone Number:ARC0457
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from A549 cells, using [KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit mAb (CAB19068) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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