The Integrin Alpha 1 (ITGA1/CD49a) Monoclonal Antibody from Assay Genie (product code: AGMAB2928) is a highly specific antibody designed for research involving integrin alpha 1, a cell surface protein involved in cell adhesion and signaling processes. This monoclonal antibody, generated using hybridomas, exhibits high reactivity with human samples and is validated for use in various applications, including flow cytometry, immunofluorescence, and immunohistochemistry.Integrin alpha 1, also known as CD49a, is a key player in cell adhesion to collagen and laminin matrices, as well as in mediating cell migration and differentiation. Its role in physiological and pathological processes such as tissue repair, angiogenesis, and cancer metastasis makes it a valuable target for investigation in various research fields, including cell biology, oncology, and tissue engineering.
This monoclonal antibody specifically binds to the integrin alpha 1 subunit, enabling precise detection and localization of this protein in different cell types and tissues. Its high specificity and sensitivity make it an essential tool for studying the function and regulation of integrin alpha 1 in normal and disease conditions, providing valuable insights into potential therapeutic strategies targeting this integrin in cancer, fibrosis, and other pathological conditions. Unlock the potential of your research with the Integrin Alpha 1 Monoclonal Antibody from Assay Genie.
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Purification Method:
Affinity purification
Gene ID:
3672
Clone Number:
ARC58198
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Integrin alpha 1 (ITGA1/CD49a) antibody (CAB22707) at 1:100000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
