The Integrin α5/ITGB5 Monoclonal Antibody (CAB23428) is a valuable tool for researchers studying integrin alpha 5, a cell adhesion molecule with key roles in cell migration, proliferation, and survival. This antibody, produced in mice, is highly specific for human samples and has been validated for use in Western blot and immunohistochemistry applications.Integrin α5/ITGB5 is a member of the integrin family of proteins, which play important roles in cell adhesion and signaling. It is involved in processes such as angiogenesis, wound healing, and tumor metastasis, making it a target of interest in cancer research and vascular biology.
By binding specifically to integrin α5, this antibody enables the detection and analysis of this protein in various cell types and tissues.Understanding the function and regulation of integrin α5 is crucial for advancing our knowledge of cell adhesion and migration mechanisms, as well as for developing potential therapeutic strategies in cancer and other diseases. The Integrin α5/ITGB5 Monoclonal Antibody (CAB23428) can aid researchers in investigating the role of integrin alpha 5 in cellular processes and disease pathology.
Product Name:
Integrin β5/ITGB5 Monoclonal Antibody
SKU:
CAB23428
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant protein of human Integrin β5/ITGB5.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
ITGB5; integrin beta-5; Integrin β5/ITGB5
Positive Sample:
A549
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Single-pass type I membrane protein.
Calculated MW:
88kDa
Observed MW:
100kDa
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.
Purification Method:
Affinity purification
Gene ID:
3693
Clone Number:
ARC60869
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts from A549, using Integrin β5/ITGB5 Rabbit mAb (CAB23428) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
