The Insulin Rabbit Monoclonal Antibody (CAB19066) is a valuable tool for researchers studying insulin, a hormone essential for regulating glucose metabolism and energy storage in the body. The antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards insulin, making it ideal for use in various immunoassays and immunohistochemistry applications.Insulin plays a crucial role in maintaining blood sugar levels and is a key player in metabolic disorders such as diabetes. By targeting insulin, researchers can gain valuable insights into insulin signaling pathways, insulin resistance, and the role of insulin in various disease conditions.
This antibody enables accurate detection and quantification of insulin in tissue samples, cell cultures, and biological fluids, facilitating research into diabetes, obesity, and other metabolic diseases.With its exceptional performance and reliability, the Insulin Rabbit Monoclonal Antibody (CAB19066) is a valuable tool for scientists working in endocrinology, metabolism, and diabetes research. Its ability to specifically recognize and bind to insulin makes it essential for studies aiming to unravel the complexities of insulin biology and its implications in health and disease.
Product Name:
Insulin Rabbit Monoclonal Antibody
SKU:
CAB19066
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Insulin (P01308).
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.
Purification Method:
Affinity purification
Gene ID:
3630
Clone Number:
ARC0209
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Insulin Rabbit mAb (CAB19066) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
