The INSRR Polyclonal Antibody (CAB10083) is a vital tool for researchers studying the insulin receptor (INSRR) protein, which plays a crucial role in regulating insulin signaling and glucose metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications.The INSRR Polyclonal Antibody specifically targets the INSRR protein, enabling precise detection and analysis in a variety of cell types. Its ability to recognize INSRR makes it an invaluable asset for studies in diabetes research, metabolic disorders, and endocrinology.
The INSRR protein is essential for mediating the effects of insulin in various tissues and organs, making it a key player in metabolic homeostasis. Dysregulation of INSRR signaling has been implicated in the development of insulin resistance, type 2 diabetes, and other metabolic conditions. By elucidating the role of INSRR, researchers can gain crucial insights into the pathophysiology of these diseases and potentially identify novel therapeutic targets for intervention.
Product Name:
INSRR Rabbit Polyclonal Antibody
SKU:
CAB10083
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 747-921 of human INSRR (NP_055030.1).
Enables transmembrane receptor protein tyrosine kinase activity. Involved in actin cytoskeleton reorganization; cellular response to alkaline pH; and protein autophosphorylation. Part of receptor complex.
Purification Method:
Affinity purification
Gene ID:
3645
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using INSRR Rabbit pAb (CAB10083) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 90s.
