INSIG2 Rabbit Polyclonal Antibody (CAB1992)
- SKU:
- CAB1992
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | INSIG2 Rabbit Polyclonal Antibody |
SKU: | CAB1992 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human INSIG2 (NP_057217.2). |
Sequence: | QIQR NVTL FPPD VIAS IFSS AWWV PPCC GTAS AVIG LLYP CIDR HLGE PHKF KREW SSVM RCVA VFVG INHA SAKV DFDN NIQL SLTL AALS IGLW WTFD R |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | INSIG-2; INSIG2 |
Positive Sample: | Mouse kidney,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 25kDa |
Observed MW: | 30kDa |
The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Purification Method: | Affinity purification |
Gene ID: | 51141 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |