The INPPL1 Polyclonal Antibody (CAB10115) is a valuable tool for researchers studying the INPPL1 protein, involved in various cellular processes such as cell growth, insulin signaling, and membrane trafficking. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for Western blot applications.INPPL1, also known as SHIP2 (SH2-containing inositol phosphatase 2), plays a crucial role in modulating insulin signaling and glucose metabolism.
Dysregulation of INPPL1 has been implicated in diseases like diabetes, cancer, and cardiovascular disorders, making it a promising target for therapeutic interventions. By using the INPPL1 Polyclonal Antibody, researchers can accurately detect and analyze the protein in different cell types, advancing studies in diverse fields such as molecular biology, biochemistry, and biomedical research.
Product Name:
INPPL1 Rabbit Polyclonal Antibody
SKU:
CAB10115
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human INPPL1 (NP_001558.3).
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
Purification Method:
Affinity purification
Gene ID:
3636
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using INPPL1 antibody (CAB10115) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
