The INPP5J Polyclonal Antibody (CAB6631) is a valuable tool for researchers studying the INPP5J protein, which is involved in phosphoinositide metabolism and cell signaling pathways. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot techniques. By targeting the INPP5J protein, this antibody allows for the detection and analysis of INPP5J in various cell types, making it suitable for studies in cell biology and signal transduction research. INPP5J is a phosphoinositide 5-phosphatase that plays a crucial role in regulating intracellular signaling cascades and membrane trafficking processes.
Dysregulation of INPP5J has been implicated in various diseases, including cancer, neurological disorders, and metabolic conditions. By understanding the function of INPP5J, researchers can gain insights into the underlying mechanisms of these diseases and potentially develop targeted therapies to treat them. Overall, the INPP5J Polyclonal Antibody is a valuable tool for researchers investigating the roles of INPP5J in cellular processes and disease pathogenesis. Its specificity and sensitivity make it a reliable choice for studies aiming to elucidate the functions of INPP5J in health and disease.
Product Name:
INPP5J Rabbit Polyclonal Antibody
SKU:
CAB6631
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1).
Predicted to enable phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate dephosphorylation; negative regulation of peptidyl-serine phosphorylation; and phosphatidylinositol dephosphorylation. Predicted to act upstream of or within negative regulation of neuron projection development. Located in cytoplasm and ruffle.
Purification Method:
Affinity purification
Gene ID:
27124
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using INPP5J antibody (CAB6631) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
