The INPP5A Polyclonal Antibody (CAB3302) from Assay Genie is specifically designed for research involving INPP5A, a phosphoinositide 5-phosphatase enzyme involved in signal transduction pathways. This antibody, raised in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the INPP5A protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in cell signaling, metabolism, and cancer research.INPP5A plays a crucial role in regulating phosphoinositide signaling, which is essential for cell proliferation, survival, and differentiation.
Dysregulation of INPP5A has been implicated in various diseases, including cancer, diabetes, and neurological disorders. Investigating the role of INPP5A in these conditions can provide valuable insights into disease mechanisms and potential therapeutic targets.Harnessing the power of the INPP5A Polyclonal Antibody from Assay Genie opens up new possibilities for understanding the intricate signaling networks involving this enzyme and its impact on cellular function. Researchers can rely on this antibody to accurately detect and quantify INPP5A levels, leading to advancements in drug discovery and personalized medicine.
Product Name:
INPP5A Rabbit Polyclonal Antibody
SKU:
CAB3302
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3).
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
Purification Method:
Affinity purification
Gene ID:
3632
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using INPP5A antibody (CAB3302) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
