The INPP4B Polyclonal Antibody (CAB16461) is a valuable tool for researchers studying the INPP4B protein, a phosphoinositide phosphatase involved in regulating cell signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to the INPP4B protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell signaling, cancer biology, and drug development.INPP4B plays a crucial role in various cellular processes, including cell growth, survival, and metabolism.
Dysregulation of INPP4B has been implicated in the development and progression of various cancers, highlighting its potential as a therapeutic target. By studying the function and expression of INPP4B, researchers can gain insights into the molecular mechanisms underlying cancer pathogenesis and identify novel strategies for targeted cancer therapy.Overall, the INPP4B Polyclonal Antibody (CAB16461) offers researchers a reliable tool for investigating the role of INPP4B in cellular signaling pathways and cancer biology, paving the way for potential advancements in precision medicine and therapeutic development.
Product Name:
INPP4B Rabbit Polyclonal Antibody
SKU:
CAB16461
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-600 of human INPP4B (NP_003857.2).
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.
Purification Method:
Affinity purification
Gene ID:
8821
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using INPP4B Rabbit pAb (CAB16461) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 150s.
