The INPP4A Polyclonal Antibody (CAB7691) is a valuable tool for researchers studying INPP4A, a phosphatidylinositol (PtdIns) signaling molecule involved in various cellular processes, including cell growth, survival, and migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.INPP4A is a critical regulator of the PI3K/Akt signaling pathway, which plays a key role in cell growth and proliferation. Dysregulation of this pathway has been implicated in cancer and other diseases, making INPP4A an important target for therapeutic intervention.
By targeting and detecting the INPP4A protein, researchers can gain insights into its function and potential role in disease progression.This antibody is suitable for immunology and cancer research, as well as for investigating the role of INPP4A in various cellular processes. Its high specificity and sensitivity make it a reliable tool for studying the functions of INPP4A and its potential as a therapeutic target in disease.
Product Name:
INPP4A Rabbit Polyclonal Antibody
SKU:
CAB7691
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human INPP4A (NP_004018.1).
This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
3631
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using INPP4A antibody (CAB7691) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
